Artemidinol — A new isocoumarin fromArtemisia dracunculus

Dracunculus Medinensis

Etymologia: Dracunculus medinensis

PM-94128, a new isocoumarin antitumor agent produced by a marine bacterium.

with 300 ml of ^2-hexane. The water-alcohol fraction was extracted twice with 300ml of CH2C12and the active CH2C12 extracts concentrated to yield 600mg. The extract was chromatographed on a silica gel column using hexane EtOAcas eluting solvent. Fractions with antitumor activity (280 mg) were eluted with w-hexane EtOAc 75 : 25. Column chromatography on silica gel was repeated and the activity (...

A New Cyclic Hexapeptide and a New Isocoumarin Derivative from the Marine Sponge-Associated Fungus Aspergillus similanensis KUFA 0013

A new isocoumarin derivative, similanpyrone C (1), a new cyclohexapeptide, similanamide (2), and a new pyripyropene derivative, named pyripyropene T (3) were isolated from the ethyl acetate extract of the culture of the marine sponge-associated fungus Aspergillus similanensis KUFA 0013. The structures of the compounds were established based on 1D and 2D NMR spectral analysis, and in the case of...

The Treatment of Dracunculus by Amarpatee

To the Editor, " Indian Medical Gazette." Sir,?I venture to send you a short note on the treatment of Dracunculas (guineaworm). I shall feel much obliged by your kindly publishing it in your widely circulated journal. It is from a very long time that the people of Dhar have been subject most frequently to Dracunculas, one of the obstinate and painful diseases. Nearly every house here has its me...